Pulmonary haemorrhage in a patient with idiopathic membranous nephropathy
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چکیده
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Treatment with rituximab in idiopathic membranous nephropathy
BACKGROUND Rituximab represents a valid therapeutic option to induce remission in patients with primary glomerulonephritis. Despite several studies proving its efficacy in improving outcomes in patients with membranous nephropathy (MN), its role in therapeutic protocols is not yet defined. METHODS We studied 38 patients with idiopathic MN treated with rituximab (in 13 patients as first-line t...
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Exciting progress recently has been made in our understanding of idiopathic membranous nephropathy, as well as treatment of this disease. Here, we review important advances regarding the pathogenesis of membranous nephropathy. We will also review the current approach to treatment and its limitations and will highlight new therapies that are currently being explored for this disease including Ri...
متن کاملPatient Age and the Prognosis of Idiopathic Membranous Nephropathy
BACKGROUND Idiopathic membranous nephropathy (IMN) is increasingly seen in older patients. However, differences in disease presentation and outcomes between older and younger IMN patients remain controversial. We compared patient characteristics between younger and older IMN patients. METHODS We recruited 171 Japanese patients with IMN, including 90 (52.6%) patients <65 years old, 40 (23.4%) ...
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Just over 50 years ago, the late David Jones1 iden tified (using the periodic acid–Schiff and meth enamine silver stains) the unique glomerular pathologic features of membranous nephropathy, thus distinguishing it from other causes of “ne phrotic glomerulonephritis.” Subsequent immuno fluorescence and electronmicroscopical studies established that membranous nephropathy was also characteri...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 1998
ISSN: 1460-2385
DOI: 10.1093/ndt/13.7.1815